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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Activation / Activators & Farnesoid X Receptor (FXR / NR1H4)

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Farnesoid X Receptor (FXR / NR1H4) activation may improve insulin sensitivity . FXR agonists induce glucagon-like peptide-1 (GLP-1). This can lower glucose levels. The signaling of the intestinal farnesoid X receptor contributes to the development of non-alcoholic fatty liver disease .
Dyson & Day 2014 Dig Dis 32: 597-604
Sattar et al. 2014 BMJ 349: g4596
Jiang et al. 2015a
Powell et al. 2021 The lancet 397: 2212-2224

Activation of Farnesoid X Receptor (FXR / NR1H4) in the [ileum](brain://fBaIP1J0LEmFy55OyXqk2…

Interactions between bile salts, gut microbiota, and hepatic innate immunity
Schubert et al. 2017 Immunological Reviews 279: 23-35
Review
Non-alcoholic fatty liver disease
Powell et al. 2021 The lancet 397: 2212-2224
Review
Non-alcoholic fatty liver disease
Sattar et al. 2014 BMJ 349: g4596
Review
The bile acid receptor FXR is a modulator of intestinal innate immunity
Vavassori et al. 2009 J. Immunol. 183: 6251–6261
Treatment of non-alcoholic fatty liver disease
Dyson & Day 2014 Dig Dis 32: 597-604
Review

5/25/2026