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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Cross-presentation

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Cross-presentation of cell-associated Ag, such as dead cell derived Ag, is a crucial process for generating CD8 T cell responses to Ag that are not expressed by APC, such as tumors of non hematopoietic origin
Lin et al. 2008

Phagocytosis is an underestimated quality of DC and this alone constitutes a very effective route of cross-presentation.
Melief, 2003…

References (Sources)

Antigen processing and remodeling of the endosomal pathway: requirements for antigen cross-presentation
Compeer et al. 2012 Front Immunol 3: 37
Review
Cross-presentation of exogenous antigens on MHC I molecules
Colbert et al. 2020 Current Opin Immunology 64: 1-8
Review
Naringenin Enhances the Antitumor Effect of Therapeutic Vaccines by Promoting Antigen Cross-Presentation
Wang et al. 2020 J Immunol 204: 622
Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming?
Melief, 2003
Review
The cell biology of cross-presentation and the role of dendritic cell subsets
Lin et al. 2008
Towards a systems understanding of MHC class I and MHC class II antigen presentation
Neefjes et al., 2011

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5/29/2026

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Cross-presentation

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