meRfi®-GM
NCT01372943 - RePOOPulate (human probiotic or synthetic stool mixture) & Clostridioides difficile infection (CDI) (recurrent)
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Fecal bacteriotherapy, commonly known as "stool transplantation," has proven effective in treating recurrent Clostridioides difficile infection (CDI). However, its widespread application is limited by concerns about donor infection transmission and patient acceptance.
Petrof et al. 2013 Microbiome 1: 3
In this study, a stool substitute preparation made from purified bacterial cultures from the gut of a single healthy donor was used to treat recurrent Clostridioides difficile infection (CDI) (recurrent) that had not responded to repeated courses of antibiotics.
P…