meRfi®-GM
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Adiposity / Obesity & Leptin
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Contents
In adiposity / obesity , a decreased sensitivity to leptin occurs (similar to insulin resistance in type 2 diabetes), resulting in an inability to detect satiety despite high energy stores and high levels of leptin
Weight loss was not significant in all the participants, although it was significant in women when analyzing both sexes separately (), and that it was associated with a significant reduction in circulating leptin level, mainly in wome…
References (Sources)
- Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms?
- GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway
- Intranasal Leptin Reduces Appetite and Induces Weight Loss in Rats with Diet-Induced Obesity (DIO)
- Leptin and gastro-intestinal malignancies (IM)
- Leptin Augments Antitumor Immunity in Obesity by Repolarizing Tumor-Associated Macrophages
- Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
- Metabolic syndrome and risk of subsequent colorectal cancer