meRfi®-GM
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Probiotics (living agents) & Depression / Depressive Disorders / Mood
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Contents
In clinical studies, Probiotics (living agents) demonstrated a greater potential than prebiotics or postbiotics in reducing symptoms of depression in patients.
However, clinical trial results are slightly disappointing
Probiotics are effective in reducing depressive symptoms when administered in addition to antidepressants (SMD = 0.83, 95%CI 0.49–1.17), however, they do not seem to offer significant benefits when used as stand-alone treatment (SMD = −0.02, 95%CI −0.34–0.30).
Nikolova et al. 2021 J. Clin. Med.10: 6…
References (Sources)
- A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome
- Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers
- Impact of consuming a milk drink containing a probiotic on mood and cognition
- Psychobiome Feeding Mind: Polyphenolics in Depression and Anxiety
- Shaping the Future of Probiotics and Prebiotics
- The Correlation Between Probiotics and Anxiety and Depression Levels in Cancer Patients: A Retrospective Cohort Study
- The Efficacy, Safety, and tolerability of probiotics on depression: Clinical results from an open-label pilot study