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Lung cancer is the leading cause of cancer-related death worldwide, with approximately 2.1 million new cases and 1.8 million deaths each year
Despite multifactorial cause, smoking remains as the major etiological factor, followed by occupational exposure to carcinogens, genetic predisposition and other concomitant diseases. Nowadays, more sensitive methods such as low-dose computed tomography are being used to improve the early detection. In the future, molecular biomarkers may complement low-dose computed tomography and improve the robustness of early lung cancer detection.
Therapeutic ad…