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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Sphingosine-1-phosphate (S1P) receptors

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Sphingosine-1-phosphate receptors, particularly Sphingosine-1 phosphate receptor 1 (S1PR1), are emerging as important modulators of pain pathways. Dysregulation of Sphingosine-1 phosphate receptor / Sphingosine-1 phosphate receptor 1 (S1PR1) signaling can lead to persistent neuroinflammation and nociceptive behaviors
Benarroch 2021 Neurology 96(11): 525-528

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References (Sources)

Cutting edge: CD69 interference with sphingosine-1-phosphate receptor function regulates peripheral T cell retention
Mackay et al. 2015 J Immunol 194: 2059-2063
What Is the Role of Sphingosine-1-Phosphate Receptors in Pain?
Benarroch 2021 Neurology 96(11): 525-528
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5/29/2026

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Sphingosine-1-phosphate (S1P) receptors

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