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Metabolomics
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Utilizing an updated NMR metabolomics platform from Nightingale Health, the study expands previous GWAS from 123 to 233 circulating metabolic traits, involving over 135,000 participants
Metabolomics means methods to study the total set of small metabolites produced by an organism. Describes metabolic profiles. Metabolomics relies heavily on the use of chromatography.
The maturation of the metagenomics field has resulted in the advancement of metabolomics methods, which are used to track microbial molecules.
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References (Sources)
- A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context
- An atlas of genetic influences on human blood metabolites
- Effects of gut microbiota on in vivo metabolism and tissue accumulation of cytochrome P450 3A metabolized drug: midazolam
- Genetic architecture of human plasma lipidome and its link to cardiovascular disease
- Genome-wide association study identifies multiple loci influencing human serum metabolite levels
- Quantitative serum nuclear magnetic resonance metabolomics in largescale epidemiology: a primer on -omic technologies
- Small molecule metabolites at the host-microbiota interface