Fecal Microbiota Transplantation (FMT) & Preclinical/Clinical data & Combinations

Fecal Microbiota Transplantation (FMT) is being extended to modulate gut microbes in patients being treated with cancer immunotherapy

• Anti-PD-1 antibodies / PD-1 inhibitors + Fecal Microbiota Transplantation (FMT)


• Enzalutamide + Fecal microbiota transplantation (FMT) + Pembrolizumab


• Fecal Microbiota Transplantation (FMT) + Immune Checkpoint Inhibitors (ICIs)


• Fecal Microbiota Transplantation (FMT) + Ipilimumab + Nivolumab


• Fecal Microbiota Transplantation (FMT) + Nivolumab


• Fecal Microbiota Transplantation (FMT) + Pembrolizumab
  to enhance responses and/or ameliorate toxicity

McQuade et al. 2020 Curr Oncol Rep 22: 74