Nose microbiota

Lactobacillus type is among the most common in our noses. The olfactory epithelium (OE) in the nose has N-acetyl heparan sulfate (NaHS) , on the ends of its nerve cells, which is different from other parts of the nose. A special type of cell, called nonsecreting murine myeloma (NS0) cell line, was previously reported to express NaHS on its cell surface and has been used as a binding target to investigate the interaction between virus proteins and the OE (Frederico et al. 2012 PLoS Pathog 8: e1002935). We used these to see how bacteria stick to NaHS and the OE. Lactobacillus bacteria stick better than others, with [Lactiplantibacillus plantarum](br…