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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Irritable Bowel Syndrome (IBS)

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Rome criteria deﬁnes 26 distinct adult functional gastrointestinal disorders (FGIDs), most well-known are irritable bowel syndrome (IBS) and
Karakan et al. 2021

Irritable bowel syndrome (IBS) is a functional disorder of the intestine whose pathophysiology is still only very incompletely understood. The prevalence of IBS is high afunctional dyspepsia (FD)nd is reported to be 4%.
Layer et al. 2021 Z. Gastroenterol. 59: 1323

Those affected suffer from abdominal pain, bloating, flatulence, diarrhea, and/or constipation. The disease is chronic and fluctuat…

References (Sources)

Advancements in drug development for diarrhea-predominant irritable bowel syndrome (IBS)
Dothel et al. 2018 Exp Opin Invest Drugs 27: 251-263
Review
Development and validation of the Rome IV diagnostic questionnaire for adults
Palsson et al. 2016 Gastroenterology. 150(6): 1481-1491
Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial
Bogovic Matijasic et al. 2016
Functional bowel disorders
Longstreth et al. 2006 Gastroenterology 130(5): 1480-1491
Review
Nerve fiber outgrowth is increased in the intestinal mucosa of patients with irritable bowel syndrome
Dothel et al. 2015 Gastroenterology 148(5): 1002-1011
Spotlight on Transition in Patients With Inﬂammatory Bowel Disease: A Systematic Review
Erős et al. 2020
Review
The functional gastrointestinal disorders and the Rome III process
Drossman 2006 Gastroenterology 130(5): 1377-1390
Review

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Irritable bowel syndrome - Wikipedia