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Epithelial stem cells sense injury signals to activate an IL-24-mediated tissue repair pathway that is molecularly distinct but functionally parallel to pathogen-induced IFN signaling in innate immunity
Interleukin-24 (IL-24) is specifically expressed by epidermal stem cells EpdSCs near the wound site
Injury-induced Interleukin-24 (IL-24) signaling resembles infection-induced IFN innate immune signaling
STAT3 activation and epithelial proliferation rely upon Interleukin-24 (IL-24) in wound repair
Epithelial Interleukin-2…