Guanine nucleotide-binding coupling proteins (G-proteins)

Heterotrimeric G proteins function to convert extracellular signals recognized by G protein-coupled receptors (GPCRs) into intracellular signaling events.
Ellaithy et al. 2020 TIBS 45: 1049

G proteins selectively stabilize a dynamic ensemble of conformations G-protein coupled receptors (GPCRs)
Manglik et al. 2015 Cell 161(5): 1101-1111
Gregorio et al. 2017 Nature 547(7661): 68-73
Latorraca et al. 2017 Chem Rev 117(1): 139-155