Adverse Events / Safety & Fecal Microbiota Transplantation (FMT)

Fecal Microbiota Transplantation (FMT) poses safety concerns, such as the possibility of spreading drug-resistant germs and causing unexpected changes in metabolism. Additionally, its composition is not stable because it depends on human donors
Alang & Kelly 2015 Open Forum Infect Dis 2: ofv004
Gupta et al. 2021 Am J Gastroenterol 116: 647-656

The risk of serious adverse events likely due to the transmission of pathogenic organisms has prompted the Food and Drug Administration to issue a safety alert regarding the use of fecal microbiota transplantation to treat patients with Clostridioides difficile infection (CDI)
Hayashi et al. 2021a

Across studies the most common adverse event has been abdominal discomfort
Wang et al. 2016a PLoS One 11: e0161174

see also:
Application & Fecal Microbiota Transplantation (FMT)
Fecal Microbiota Transplantation (FMT)
Fecal Microbiota Transplantation (FMT) & Clostridioides difficile infection (CDI) (recurrent)
Fecal Microbiota Transplantation (FMT) & Pouchitis
Fecal Microbiota Transplantation (FMT) & Regulations