meRfi®-GM

PAC-113 is a synthetic peptide consisting of 12 amino acids, designed to mimic the active region of histatin. Its sequence is AKRHHGYKRKFH, which gives it a net positive charge. This cationic nature is a key feature of many antimicrobial peptides, as it allows them to interact with and disrupt microbial cell membranes.

PAC-113 has demonstrated broad-spectrum antimicrobial activity against various pathogens, including:

• Bacteria (both Gram-positive and Gram-negative)


• Fungi


• Yeasts

Its effectiveness has been particularly noted against oral pathogens such as Candida albicans, Streptococcus mutans, and Porphyromonas gingivalis. This makes PAC-113 a promising candidate for treating oral infections and maintaining oral health.
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