meRfi®-GM
Afatinib
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Afatinib binds irreversibly to HER1/EGFR/ErbB-1 (epidermal growth factor receptor), HER1/EGFR/ErbB-1 (epidermal growth factor receptor) (MUT), HER2/neu/EGFR2/ERBB2 (MUT). It has therapeutic potential for cancers with ERBB2 (HER2) transmembrane domain mutations G660D and V659E
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