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It is hard to separate the link between Chlamydia trachomatis and Bacterial vaginosis. Both are affected by sexual behaviors.
Chlamydia trachomatis causes widespread bacterial infection, yet the components underlying its pathogenicity are not fully understood. Walsh et al. describe a new host-pathogen axis involving the bacterial effector gamma resistance determinant (GarD) as a key to avoid immune detection and destruction driven by the human protein RNF213. This obligate intracellular pathogen resides and replicates within a cellular compartment termed an inclusion
Walsh et al. 2022 Cell Host & Microbe 30(12): 167…