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now being considered as a backup suicide
mechanism when caspase-dependent apoptosis is inhibited
Necroptosis is induced by death receptors independently of caspases but dependent on RIPK1 & RIPK3
Necroptosis is an inflammatory cell death mode that regulates tumor growth through cell death-dependent and independent mechanisms.
Rucker & Ka-Ming Chan 2022 Trends in Biochemical Sciences 47: 342…