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The enterochromaffin cells (ECs) are the main producers of melatonin in the gastrointestinal (GI) tract. Initially identified in the Pineal gland, melatonin is now recognized as being synthesized throughout the GI tract, from the stomach to the colon. The Enterochromaffin Cells (EC) are known to produce several hundred times more melatonin than the amount produced by the pineal gland.
[Melatonin](brain://LKVc…