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Enterochromaffin Cells (EC) & Melatonin
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Contents
The enterochromaffin cells (ECs) are the main producers of melatonin in the gastrointestinal (GI) tract. Initially identified in the Pineal gland, melatonin is now recognized as being synthesized throughout the GI tract, from the stomach to the colon. The Enterochromaffin Cells (EC) are known to produce several hundred times more melatonin than the amount produced by the pineal gland.
[Melatonin](brain://LKVc…
References (Sources)
- A Focus on Enterochromaffin Cells among the Enteroendocrine Cells: Localization, Morphology, and Role
- Enterochromaffin cells as the souce of melatonin: Key findings and functional relevance in mammals
- Melatonin may be synthesised in enterochromaffin cells
- Melatonin signaling in mitochondria extends beyond neurons and neuroprotection: Implications for angiogenesis and cardio/gastroprotection
- Putative tissue location and function of the SLC5 family member SGLT3
- Thirty four years since the discovery of gastrointestinal melatonin