meRfi®-GM
Metabolic Pathways
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Contents
Cell survival, proliferation and function are energy-demanding processes, fuelled by different metabolic pathways. Glycolysis is typically the “pro-inflammatory immuno-metabolic pathway” characteristic of T helper (Th)-1, Th17 cells, pro-inflammatory macrophages (M1) and activated dendritic cells (DC)
Lactate has been shown to dampen the activity of innate immune cells such as monocytes and [macrophage…