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Central Nervous System (CNS) is composed of the brain and spinal cord
The idea of CNS immune privilege, which was once believed to separate the mammalian brain from the body's immune system, has changed. Research now shows that immune cells play beneficial roles in both CNS health and disease. Additionally, there are physical pathways that allow communication between the CNS and the immune system. Vascular channels directly connect the skull bone marrow to the brain surface, allowing for the migration of myeloid cells.
Microglia, the …