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Central Nervous System (CNS)
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Central Nervous System (CNS) is composed of the brain and spinal cord
The idea of CNS immune privilege, which was once believed to separate the mammalian brain from the body's immune system, has changed. Research now shows that immune cells play beneficial roles in both CNS health and disease. Additionally, there are physical pathways that allow communication between the CNS and the immune system. Vascular channels directly connect the skull bone marrow to the brain surface, allowing for the migration of myeloid cells.
Microglia, the …
References (Sources)
- Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration
- Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood
- Microglia as therapeutic targets after neurological injury: strategy for cell therapy
- The gut microbiota–brain axis in behaviour and brain disorders
- Tissue-resident memory T cells populate the human brain
- Understanding the role of T cells in CNS homeostasis