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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Bile acids / Bile salts & Farnesoid X receptor (FXR / NR1H4)

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
Goodwin et al. 2000 Mol. Cell 6: 517-526
Bile acids: natural ligands for an orphan nuclear receptor
Parks et al. 1999 Science 284: 1365-1368
Bile-acid-activated receptors: Targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders
Fiorucci et al. 2009 Trends Pharm. Sci. 30: 570-580
Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism
Wahlström et al. 2016 Cell Metab. 24: 41-50
LXRS and FXR: the yin and yang of cholesterol and fat metabolism
Kalaany et al. 2006 Annu. Rev. Physiol. 68: 159-191
Review
Role of Bile Acids in the Regulation of Food Intake, and Their Dysregulation in Metabolic Disease
Xie et al. 2021a
Review
The Bile Acid Sensor Farnesoid X Receptor Is a Modulator of Liver Immunity in a Rodent Model of Acute Hepatitis
Mencarelli et al. 2009 J. Immunol. 183: 6657-6666

5/29/2026