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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Claudins (claudin family proteins)

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Claudins have a greater role in controlling the “pore pathway” or paracellular ﬂux of ions and small molecules

Mitic et al. 2000 Am J Physiol Gastrointest Liver Physiol 279(2): G250-4
Van Itallie & Anderson 2004 Physiol (Bethesda) 19: 331-8
Van Itallie & Anderson 2014 Semin Cell Dev Biol 36: 157-65
König et al. 2016 Clin Transl Gastroenterol 7(10): e196
Ma et al. 2018a In: Physiology of the Gastrointestinal Tract: Sixth Edition. London, United Kingdom, San Diego, CA, United States, Cambridge, MA, United States, Kidlington, United Kingdom: Elsevier Inc 587-639. 1-2.

The family of claudin consists of 27 proteins and plays an important role in the maintenance of cell polarity and transportation, and are necessary for the strong binding of epithelial and endothelial cells

Niessen 2007 J Invest Dermatol 127: 25…

References (Sources)

Architecture of Tight Junctions and Principles of Molecular Composition
Van Itallie & Anderson 2014 Semin Cell Dev Biol 36: 157-65
Review
Claudin-1 and -2: Novel Integral Membrane Proteins Localizing At Tight Junctions With No Sequence Similarity to Occludin
Furuse et al. 1998 J Cell Biol 141: 1539-50
Claudins and Epithelial Paracellular Transport
Van Itallie & Anderson 2006 Annu Rev Physiol 68: 403–29
Review
Human Intestinal Barrier Function in Health and Disease
König et al. 2016 Clin Transl Gastroenterol 7(10): e196
Review
The claudin family of proteins in human malignancy: A clinical perspective
Ding et al. 2013 Cancer Manag Res 5: 367-375
Review
Tight Junctions and the Intestinal Barrier
Ma et al. 2018a In: Physiology of the Gastrointestinal Tract: Sixth Edition. London, United Kingdom, San Diego, CA, United States, Cambridge, MA, United States, Kidlington, United Kingdom: Elsevier Inc 587-639. 1-2.
Tight junctions/adherens junctions: basic structure and function
Niessen 2007 J Invest Dermatol 127: 2525-2532
Review

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Claudin - Wikipedia