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Distal Colon / Colon / Large Intestine

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In the large intestine, adult stem cells reside within the invaginations and constantly proliferate.
Kayisoglu et al. 2021

The colon is the most densely populated area of the digestive tract , with 10H12 cells per gram of intestinal substance comprised of up to 1000 different species
Shapira 2016 Trends Ecol Evol. 31(7):539-549
Gomaa 2020 Antonie Van Leeuwenhoek 113(12): 2019-2040

Bacteroides and Clostridiales become the dominating members in the colon
Kim et al. 2017 Immunol Rev. 279(1): 90-105

The colon microbiota is primarily powered by the efficient breakdown of complex indigestible carbohydrates.
Marchesi et al. 2016 Gut 65: 330‑339

In the hum…