meRfi®-GM
G-Protein Coupled Receptor 41 (GPR41)
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Contents
G-Protein Coupled Receptor 41 (GPR41) is expressed by
• Enterocytes / Intestinal Epithelial Cells (IECs)
• Immune cells
• enteroendocrine L cells in the gut epithelium
to produce several effects that might impact liver metabolism.
Loss of G-Protein Coupled Receptor 41 (GPR41) signaling and decreased serum levels of PYY promote intestinal peristalsis and reduce energy procurement from [food](brain://NMz_R1EmnUiyI_QfLe9-Rw/…
References (Sources)
- Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms
- Butyrate-induced GPR41 activation inhibits histone acetylation and cell growth
- Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
- Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
- Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
- Gut microbiota, metabolites and host immunity
- Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2