Loading…

Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

ST6GalNAc I sialyltransferase (ST6GALNAC1)

Welcome to meRfi-GM!

Please register to continue your trial period!

meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

ST6GalNAc I associated with increased sialylation of the abberant O-glycan Tn to Sialyl-Tn and associated with MUC1 expression

Biosynthesis of Sialyl-Tn (STn) / Neu5Acα2-6GalNAc-O-Ser/Thr is mediated by a specific sialyltransferase termed ST6GalNAc I
Julien et al., 2012
…

Cloning and expression of a human gene encoding an N-acetylgalactosamine-α2,6sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens
Ikehara et al.1999
Correlation analysis between tumor-associated antigen sialyl-Tn expression and ST6GalNAc I activity in human colon adenocarcinoma
Vazquez-Martin et al., 2004
Cross-talk between Colon Cells and Macrophages Increases ST6GALNAC1 and MUC1-sTn Expression in Ulcerative Colitis and Colitis-Associated Colon Cancer
Kvorjak et al. 2020 Cancer Immunology Research 8: 167
Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA
Julien et al. 2001
RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells
Tamura et al., 2016
Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen.
Marcos et al., 2004
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues
Marcos et al. 2011 Front Biosci (EliteEd) 3: 1443–55

12/16/2025