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Histone Acetylation / Histone Acetyltransferase increases gene expression. Histone acetylation is linked to transcriptional activation and associated with euchromatin. Euchromatin, which is less densely compact, allows transcription factors to bind more easily to regulatory sites on DNA, causing transcriptional activation
Modulation of the Activity of Enzymes and Transcription Factors Including the Histone Acetyltransferase and Deacetylase and the Hypoxia-inducible Factor
Corrêa-Oliveira et al. 2016 Clin. Transl. Immunol. 5: e73…