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Histone acetylation / Histone acetyltransferase (HAT)
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Contents
Histone Acetylation / Histone Acetyltransferase increases gene expression. Histone acetylation is linked to transcriptional activation and associated with euchromatin. Euchromatin, which is less densely compact, allows transcription factors to bind more easily to regulatory sites on DNA, causing transcriptional activation
Modulation of the Activity of Enzymes and Transcription Factors Including the Histone Acetyltransferase and Deacetylase and the Hypoxia-inducible Factor
Corrêa-Oliveira et al. 2016 Clin. Transl. Immunol. 5: e73…
References (Sources)
- A Review on Important Histone Acetyltransferase (HAT) Enzymes as Targets for Cancer Therapy
- Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats
- The Brain Epigenome Goes Drunk: Alcohol Consumption Alters Histone Acetylation and Transcriptome
- The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation.