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The meninges consist of three membranes (dura, arachnoid and pia) that protect the central nervous system (CNS) from injury and infection.
A repertoire of innate and adaptive immune cells reside within the dural meninges that have roles in tissue repair, antigen sampling and host defence.
The meninges are innervated by trigeminal ganglia (TG) nociceptors that drive [headache](brain://_Ba…