Toll-like receptor 8 (TLR-8)

What is TLR-8?

endosomal localisation

On which human immune cells is TLR-8 found?

myeloid dendritic cells (mDCs), T cells, Monocytes, NK cells
Shekarian et al. 2017 Ann Oncol. 28(8): 1756-1766

On which human non-immune cells is TLR-8 found?

What are the ligands of TLR-8?

The Toll-like receptor 8 (TLR8) is a critical sensor for viable bacteria, ssRNA viruses, and archaea in human antigen-presenting cells (APC).
Ugolini & Sander 2019

see also:

Toll-like receptor 8 (TLR-8) agonists