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Isopentenyl pyrophosphate (IPP)

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Isopentenyl pyrophosphate (IPP) is a key molecule in isoprenoid (a diverse class of over 30,000 natural products) biosynthesis.
Lombard & Moreira 2011 Mol Biol Evol. 28(1): 87-99

It consists of a five-carbon (isopentenyl) unit attached to a pyrophosphate group

The synthesis of Isopentenyl pyrophosphate (IPP) occurs via the HMG-CoA reductase (HMGCR) (pathway) or the Methylerythritol phosphate (MEP) pathway (also known as the non-mevalonate pathway).

The HMG-CoA reductase (HMGCR) (pathway) is predominantly found in [eukaryotes](brain://WfBQdDjMdFqkdW-M65YJ2Q/Euka…