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Amyloids
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Contents
Amyloids are aggregates of proteins characterized by a fibrillar morphology of 7–13 nm in diameter.
80 Amyloid Protein Fibrils, both Pathogenic and Functional
Even stranger, a single protein sequence can adopt completely different two-dimensional conformations, resulting in different fibril polymorphs
In contrast to globular proteins, amyloid proteins are flattened and stack up into unbranched fibrils
Thus, an amyloid protein can define various diseases depending on its conformation
Bacterial Amyloids through Molec…