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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Bacteroides & Polysaccharide utilization loci (PULs)

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Bacteroides possess an extraordinary repertoire of polysaccharide utilization loci (PULs) that facilitate the breakdown of complex host-derived glycans, including Human Milk Oligosaccharides (HMOs).
Marcobal et al. 2011 Cell Host Microbe. 10: 507-514
Lapébie et al. 2019 Nat. Commun. 10: 2043
La Rosa et al. 2022 Curr. Opin. Microbiol. 67: 102143

Bacteroides fragilis and Bacteroides thetaiotaomicron are known to possess Polysaccharide utilization loci (PULs), which mediate the foraging of intestinal [mucus](br…

References (Sources)

Bacterial colonization factors control specificity and stability of the gut microbiota
Lee et al. 2013 Nature 501: 426-429
Bacteroides in the infant gut consume milk oligosaccharides via mucusutilization pathways
Marcobal et al. 2011 Cell Host Microbe. 10: 507-514
Glycan processing in gut microbiomes
La Rosa et al. 2022 Curr. Opin. Microbiol. 67: 102143
Gut microbiota utilize immunoglobulin A for mucosal colonization
Donaldson et al. 2018 Science 360: 795-800
Navigating the gut buffet: control of polysaccharide utilization in Bacteroides spp.
Schwalm & Groisman 2017 Trends Microbiol 25: 1005-1015
Review
Polysaccharide utilization loci in Bacteroides determine population ﬁtness and community-level interactions
Feng et al. 2022 Cell Host & Microbe 30: 200-215
Symbiotic Human Gut Bacteria with Variable Metabolic Priorities for Host Mucosal Glycans
Pudlo et al. 2015 mBio 6: e01282-e01215

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Bacteroides & Polysaccharide utilization loci (PULs)

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