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Warburg effect
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Contents
Diagnostically the Warburg effect is the basis for the PET scan in which an injected radioactive glucose analog is detected at higher concentrations in malignant cancers than in other tissues.
The preference of cancer cells to use glucose for biomass buildup rather than for energy production is known as the Warburg effect
Warburg 1956 Science 123: 309–314
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References (Sources)
- 17 beta‑estradiol‑induced mitochondrial dysfunction and Warburg effect in cervical cancer cells allow cell survival under metabolic stress
- Pyruvate kinase M2 regulates Hif‑1 α activity and IL‑1β induction and is a critical determinant of the Warburg effect in LPS‑activated macrophages
- The immunological Warburg effect: Can a metabolic-tumor-stroma score (MeTS) guide cancer immunotherapy?Review
- The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation.