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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Akkermansia

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Akkermansia can lower the permeability of the mucosal barrier by stimulating the production of intestinal mucus and tight junction proteins
Rohr et al. 2020

The Akkermansia genus belongs to the Verrucomicrobia phylum
Schroeder & Bäckhed 2016 Nat Med. 22: 1079-89

References (Sources)

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inﬂammation in association with increased Akkermansia spp. population in the gut microbiota of mice
Anhe et al. 2015 Gut 64: 872
Gut Microbiota Modulation through Akkermansia spp. Supplementation Increases CAR T-cell Potency
Marcos-Kovandzic et al. 2025 Cancer Discovery 15(9): 1905
Negative Effects of a High-Fat Diet on Intestinal Permeability: A Review
Rohr et al. 2020
Review
Signals from the gut microbiota to distant organs in physiology and disease
Schroeder & Bäckhed 2016 Nat Med. 22: 1079-89
Review
The Biology of Akkermansia
Hughes et al. 2025 Annu Rev Microbiol 79: 287-310
Review

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5/29/2026

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Akkermansia - Wikipedia