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The primary medication used to treat Morbus Parkinson / Parkinson's Disease (PD) is Levodopa (L-DOPA). For L-dopa to be effective, it must enter the brain and be converted into the neurotransmitter dopamine by the human enzyme Aromatic-L-amino-acid-decarboxylase (DDC)
However, a significant challenge arises because the gastrointestinal tract is also a major site for L-dopa decarboxylation. This peripheral metabolism is problematic since [dopamine](brain://Z1ibgm_7t0m…