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Liver X-Receptors (LXRs)

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Dimer: LXR/RXR

LXR is one of the transcription factors and occurs in the isoforms LXR alfa and LXR beta
Lefort & Cani 2021

Liver X-receptors (LXRs) are critically involved in atherogenesis
Savla et al. 2022 Expert Opinion on Therapeutic Targets 26(7): 645-658

The anti-atherogenic effect mediated via Liver X-Receptors (LXRs) is attributed to the inhibition of Macrophage-Mediated Inflammation and promotion of reverse cholesterol transport
Savla et a…