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Axial spondyloarthritis (AxSpA) is an inflammatory disease of the joints, entheses, and bone tissue. It is sometimes associated with psoriasis, anterior uveitis, and intestinal inflammation.
Abnormal differentiation of CD4+ T cells and enhanced type 3 immune response are essential in their pathogenicity. Therefore, Interleukin (IL)-17- and Janus kinase inhibitors are being developed for treatment beyond [tumor necrosis factor alfa inhibition](brain://3sH7VGpweUCj4sIlHOxz8Q/TumorNecrosisFactorAlfaTNFalfaAntibodiesTumorNecr…