Antibiotics & Human Microbiota / Human microbiome

Antibiotic treatment is the standard way to induce dysbiosis, characterized by four aspects: loss of critical taxa, loss of diversity, changes in metabolic activity, and development of a pathogenic microflora
Vangay et al. 2021 Cell Host Microbe 17: 553-564

Our study demonstrates that administration of broad-spectrum antibiotics in adolescent mice for two weeks resulted in higher mortality and lower weight gain and induced significant changes in behavior of animals including decreased locomotor and exploratory activity, reduced muscle strength, visceral hypersens…