meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Antibiotics & Human Microbiota / Human microbiome
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Contents
Antibiotic treatment is the standard way to induce dysbiosis, characterized by four aspects: loss of critical taxa, loss of diversity, changes in metabolic activity, and development of a pathogenic microflora
Our study demonstrates that administration of broad-spectrum antibiotics in adolescent mice for two weeks resulted in higher mortality and lower weight gain and induced significant changes in behavior of animals including decreased locomotor and exploratory activity, reduced muscle strength, visceral hypersens…
References (Sources)
- A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics
- Allergies and Asthma: Do Atopic Disorders Result from Inadequate Immune Homeostasis arising from Infant Gut Dysbiosis?
- Antibiotics, pediatric dysbiosis, and disease
- Immune-Microbiota Interactions: Dysbiosis as a Global Health Issue
- Protective Effects of Probiotics on Cognitive and Motor Functions, Anxiety Level, Visceral Sensitivity, Oxidative Stress and Microbiota in Mice with Antibiotic-Induced Dysbiosis
- Recovery of the Gut Microbiota after Antibiotics Depends on Host Diet, Community Context, and Environmental Reservoirs
- The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor?