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Biological effects / Functions & Interleukin-23 (IL-23)
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Interleukin-23 (IL-23) plays a significant role in T cell activation and stimulates the expansion and survival of T helper 17 cell (Th17). Interleukin-23 (IL-23) has been implicated in airway inflammation mediated by Type 2 cytokines and type 17 cytokines.
The polarization to a T helper 17 cell (Th17) phenotype is initially triggered by Interleukin-6 (IL-6) and [Transforming growth factor beta (TGF-beta)](brain://0HQPXyRXdkGdJCNrmGbUFw/TransformingGrowthFactor…