Non-Alcoholic Fatty Liver Disease (NAFLD) / Metabolic dysfunction-associated fatty liver disease (MAFLD)

Non-Alcoholic Fatty Liver Disease (NAFLD) / Metabolic dysfunction-associated fatty liver disease (MAFLD) is one of the most common and increasing liver diseases worldwide with a prevalence of 20–33%. NAFLD may progress to fibrosis, compensated cirrhosis, advanced cirrhosis, or hepatocellular carcinoma (24).

In 1980, the term non-alcoholic fatty liver disease (NAFLD) was introduced to describe the occurrence of fatty liver disease without the presence of other chronic liver diseases or alcohol consumption exceeding 140 grams per week for women and 210 grams per week for men. Recently, due to the frequent association of NAFLD with dysmetabolic comorbidities, it has been renamed to metaboli…