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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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3-Hydroxybutyrate / beta-Hydroxybutyric acid (BHB)

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3-Hydroxybutyrate / beta-Hydroxybutyric acid (BHB) has a structure and role in regulating gut homeostasis and gene expression through epigenetic modiﬁcations similar to butyrate, both of which may have therapeutic roles in treating inﬂammation-related diseases, such as obesity and asthma, in children
Alsharairi 2020 Int. J. Mol. Sci. 21: 9580
Alsharairi 2021 Nutrients 13: 3702

3-Hydroxybutyrate / beta-Hydroxybutyric acid selectively inhibits biﬁdobacterial growth
Ang et al. 2020 Cell 181: 1263–1275

The level of circulating 3-Hydroxybutyrate / beta-Hydroxybutyric acid (BHB) is known to…

References (Sources)

In vitro human colonic microbiota utilises D- β -hydroxybutyrate to increase butyrogenesis
Sasaki et al. 2020 Sci. Rep. 10: 8516
Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells
Ang et al. 2020 Cell 181: 1263–1275
Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation
Singh et al. 2019a Gut 68(10): 1801-12
The role of short-chain fatty acids in mediating very low-calorie ketogenic diet-infant gut microbiota relationships and its therapeutic potential in obesity
Alsharairi 2021 Nutrients 13: 3702
The role of short-chain fatty acids in the interplay between a very low-calorie ketogenic diet and the infant gut microbiota and its therapeutic implications for reducing asthma
Alsharairi 2020 Int. J. Mol. Sci. 21: 9580
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3-Hydroxybutyrate / beta-Hydroxybutyric acid (BHB)

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