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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Caspases (cysteine-dependent aspartate-specific proteases)

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Caspase Activation Has the Ability to Expose Neo-epitopes through the Direct Cleavage of Proteins, Which Results in Epitopes from These Proteins Being Favored for Cross-presentation

At Least 13 Members of the Caspase Family Have Been Identitied
Mouawad et al., 2002
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References (Sources)

A Review on Caspases: Key Regulators of Biological Activities and Apoptosis
Sahoo et al. 2023 Mol Neurobiol. 60(10): 5805-5837
Review
Caspase functions in cell death and disease
McIlwain et al. 2013 Cold Spring Harb Perspect Biol. 5(4): a008656
Caspases and their substrates
Julien & Wells 2017 Cell Death Differ 24: 1380-1389
Review
Cellular mechanisms controlling caspase activation and function
Parrish et al. 2013 Cold Spring Harb Perspect Biol. 5(6): a008672
Making the head: Caspases in life and death
Svandova et al. 2023 Front Cell Dev Biol. 10: 1075751
Review
Old, new and emerging functions of caspases
Shalini et al. 2015 Cell Death Differ 22: 526-539
Review
Serum caspase-1 levels in metastatic melanoma patients: relationship with tumour burden and nonresponse to biochemotherapy
Mouawad et al., 2002

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2/26/2026

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Caspases (cysteine-dependent aspartate-specific proteases)

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