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Toxins are vital in ecological interactions, serving as tools for predation and defense in various species like snakes, spiders, and Cone snails. Despite their potential harm to humans, toxins are crucial in scientific research, aiding in the study of physiological and pharmacological processes such as synaptic transmission and ion channel subtypes (1).
The use of toxins as experimental tools in physiology has a rich history. In the 1800s, Claude Bernard utilized curare to demonstrate the existence of chemical signaling between nerves and muscles (2).
Similarly, Henry Dale employed [muscarin…