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Chemokines
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Chemokines are small (about 100 amino acids, 8-14 kDa), chemoattractant proteins that stimulate the migration and activation of cells, especially from phagocytic cells and lymphocytes. Chemokines have a central role in inflammatory responses
Murphy 2022 W.W. Norton & Company ISBN 978-0-393-68093-5
Chemokines are chemotactic cytokines that regulate the migration of immune cells. Chemokines function as cues for the coordinated recruitment of immune cells into and out of tissue. They also guide the spatial organization and cellular interactions of immune cells within tissues.
Ozga et al. 2…
References (Sources)
- A Galectin-3-Dependent Pathway Upregulates Interleukin-6 in the Microenvironment of Human Neuroblastoma
- Biomolecular Network Reconstruction ldentifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer
- Chemokine receptor CXCR4-dependent internalization an resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells
- Chemokines and the immune response to cancer
- How do stem cells find their way home?
- Janeway’s Immunobiology 10th
- The signicance of chemokines in diffuse large B-cell lymphoma: a systematic review and future insights