meRfi®-GM
Cytotoxic T cell (CTL)
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Contents
Key features: Pathogens such as viruses, some intracellular bacteria target CD8+ T-Cell / Cytotoxic T Cell (CTL)
Effector molecules: Perforin / Perforin-1, Granzymes, Granulysin, Fas ligand (FasL), IFN gamma (often), Lymphotoxin alfa (LT alfa), [TNF alfa](brain://roB44vrlq0CAuRxhHTN9XQ/TumorNecrosis…
References (Sources)
- A guide to immunometabolism for immunologists
- CD8 T cells and mTOR: new concepts and targets for systemic lupus erythematosus
- Direct activation of CD8 + cytotoxic T lymphocytes by dendritic cells
- Does T Cell Activation Require a Quorum of Lymphocytes?
- Helper activity is required for the in vivo generation of cytotoxic T lymphocytes
- Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine
- Second- and third-generation drugs for immuno-oncology Treatment - The more the better?