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CD80

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B7-1 is a cell surface protein on specialized antigen-presenting cells such as dendritic cells and which is a major costimulatory molecule for T cells. It is a closely related member of the immunoglobulin superfamily (B7-CD28 immune checkpoint family group I), and binds to the CD28 and Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) on [T cells](brain://ejbC3Yxj_UC-rY5BzIgK6w/TCellsTCellsTLymphoc…